Phage therapy in vivo – how important is the host’s immune response?
Researchers have demonstrated that the efficacy of phage therapy is dependent on synergy with the host’s immune system.
Browsing: Bacteriophage
Think broad, act narrow: bacteriophage therapy, a targeted solution to GBS?
Widespread use of antibiotics in pregnancy to eradicate Group B Streptococcus has reduced disease in babies, however, could bacteriophage therapy yield the same results but in a more selective manner?
Hybrid phage particles could increase bacterial host range
A team from Tel Aviv University have developed hybrid bacteriophage particles that may allow DNA transduction to new bacteria, expanding the range of currently used phages.
Phages and immunomodulation
This article discusses evidence for phage engagement in regulating immunity, shedding new light on the potential immunoregulatory activities of phages which constitute an abundant part of the microbiome.
Lysibodies – a promising new weapon against drug-resistant bacteria?
Components from bacteria-infecting viruses could allow scientists to create hybrid human antibodies that can target carbohydrate molecules found on bacterial cell surfaces.
Bacteriophages provide promising results against multidrug-resistant E.coli
Research has suggested that bacteriophages derived and manipulated from ExPEC reservoirs are capable of combating infections caused by E.coli ‘superbugs’.