While sepsis is well defined clinically, the molecular immunological mechanisms that underlie the development of sepsis are poorly understood.
DNA sequencing of MRSA could help identify patients who are most at risk of death from the infection – providing a new treatment strategy towards personalized medicine.
Recently, the use of small molecules produced by bacteria became a prominent strategy of biofilm dispersal. Here, the authors discuss small molecules that interfere with biofilm formation, focusing on the complex mode of action and applications of D-amino acids.
Could nanoconstructs be utilized to fight infection? This Editorial discusses the potential of photoactivatable nanodrugs to overcome the growing problem of acquired antibiotic resistance in bacteria as well as the intrinsic resistance of biofilm-associated infections.