Experimental antimalarial shows promise in human challenge study
A single, oral dose of antimalarial DSM265 has cleared seven volunteers of a Plasmodium falciparum infection, according to the trial from the Medicines for Malaria Venture.
Browsing: Clinical Trial
FDA accepts two NDAs from Merck for Priority Review: February’s industry headlines
Take a look at this month’s industry headlines including Priority Review for two antibacterial agents from Merck (NJ, USA), a clinical trial for a new malaria drug and the launch of omadacycline in the USA.
New treatments for onchocerciasis – the current clinical pipeline
Some of the challenges with mass ivermectin administration could be addressed with new drugs or drug combinations with higher effect for the parasite – leading us to ask, what new treatments are currently in the clinical pipeline?
First US clinical trial for intravenous phage therapy gets FDA approval
A first for clinical trials in the US as researchers from the University of California San Diego School of Medicine get US FDA approval to use intravenously-administered bacteriophage therapy in hopes of combatting resistant bacteria.
First-ever multi-drug Ebola trial launched in the Democratic Republic of Congo
A new trial has begun in the Democratic Republic of Congo, aiming to collect robust data on the safety and efficacy of investigational Ebola therapeutics.
Gastroenteritis in children unscathed by treatment with probiotics
Concurrent major US and Canadian clinical trials prove probiotics to be ineffective in combatting gastroenteritis in children.
Novel antibiotic effective in the treatment of uncomplicated gonorrhea in Phase II trial
A Phase II, muti-center, randomized, open-label trial has reported that a novel oral antibiotic, zoliflodacin, is effective in the treatment of uncomplicated urogenital gonorrhea.
Shorter treatment duration a possibility for pulmonary TB
New data analysis of three clinical trials has suggested that a precision medicine approach could allow some pulmonary TB patients to have significantly shorter treatment periods.
Investigational antibiotic effective against drug-resistant UTIs in Phase II trial
A Phase II trial has demonstrated that a new investigational antibiotic, cefiderocol, is as effective as the current standard-of-care for treating complicated UTIs caused by multi-drug resistant bacteria.
FDA approves Xofluza™, the first single-dose oral medicine for influenza
Roche has announced the FDA approval of Xofluza™, the first and only single-dose oral medicine approved to treat flu.