The role of public health in precision medicine – an interview with Kelly Gebo
In this interview we speak to Kelly Gebo, Chief Medical and Scientific Officer for the…
Browsing: Genomics
Novel parasites and understanding parasite–host interactions – an interview with Sandra Maruyama
In October 2019 researchers from Brazil identified a new parasite, which presented with similar symptoms to visceral leishmaniasis. To discover more about this novel parasite and other parasitic diseases in Brazil, we interviewed Sandra Maruyama from the Federal University of São Carlos (UFSCar; São Paulo, Brazil) about her research and the future of this field.
The Malaria Cell Atlas provides insights into gene clusters and future treatments
Researchers recently profiled the single-cell transcriptomes of thousands of individual parasites to provide the first high-resolution atlas of malaria parasite gene expression across the lifecycle.
Malaria: genomic surveillance detects multi-drug resistance has spread in Asia
Multidrug resistance to two antimalarials, used in combination as a first-line therapy, has been found using genomic surveillance to be rapidly spreading throughout Asia.
CRISPR and long-acting therapies eliminate HIV DNA from the genome in animal models
A new study using CRISPR-Cas9 and long-acting slow-effective release antiretroviral therapy has reported the elimination of replication-competent HIV-1 DNA from the genomes of living animals for the first time.
ASM Microbe: Antibiotic-resistant probiotic Bacillus strains discovered
Scientists at California State University, Fresno have identified multidrug resistance in six probiotic Bacillus strains to several antibiotics through genetic analysis.
What influence could genetics have on immunity following vaccination?
A study has revealed genetic variants associated with differing levels of protective antibodies produced after routine immunizations.
First genomic description of global S. pneumoniae population released
A global genomic survey of Streptococcus pneumoniae has identified 621 strains across 50 countries and has highlighted how the bacteria can evolve in response to vaccination.
How can genomics help us understand carriage and invasive disease in N. meningitidis? – an interview with Sarah Earle
In this interview we speak with Sarah Earle from the University of Oxford (UK) about her use of GWAS to understand more about Neisseria meningitidis and its transition from an asymptomatic commensal to an invasive pathogen.
Group A Streptococcus sequencing reveals potential targets for a global vaccine
A cohort of scientists from the Wellcome Sanger Institute, the University of Cambridge, the Peter Doherty Institute for Infection and Immunity and the University of Queensland have identified novel targets using DNA sequencing, bringing research one step closer to developing a universal vaccine against Group A Streptococcus.