Researchers at the University of Toronto have revealed the binding action of the bacterial toxin responsible for toxic shock syndrome. Although similar to the toxin that causes diarrhea, the two proteins behave differently due to a short amino acid sequence, which the researchers were able to manipulate.
Browsing: Host-pathogen Interaction
A team of researchers have uncovered a protein, AGO4, which may have the potential to be used as a therapeutic target to universally increase protection against viral pathogens.
In October 2019 researchers from Brazil identified a new parasite, which presented with similar symptoms to visceral leishmaniasis. To discover more about this novel parasite and other parasitic diseases in Brazil, we interviewed Sandra Maruyama from the Federal University of São Carlos (UFSCar; São Paulo, Brazil) about her research and the future of this field.
In this interview, we speak to Jenn Edwards from the Abigail Wexner Research Institute (OH, USA) about her research using the primary human epithelial cell models to examine Neisseria gonorrhoeae infections, the potential for vaccination against gonorrhea and a possible host-targeted therapy for this infection.
Researchers have uncovered a novel mechanism utilized by group A streptococcus that allows it to evade detection by the immune system in infected mice, providing insight for the development of effective countermeasures against this pathogen.
New research indicates that harnessing RNA sensors could allow human cells to be more attuned to killing tuberculosis, presenting an effective means for controlling the spread of the disease.
In this opinion piece we take a look at the interaction of bacteria, phages and the human immune system. asking how these three components each play a role in phage therapy?
Researchers may have discovered how Ebola invades our immune system and disrupts the host immune response.
Rotavirus infection can result in severe-life threatening illness in some individuals, however, new research from a team at Georgia State University (GA, USA), has identified bacteria that could be used to prevent or cure this infection.
Researchers at Dartmouth’s Geisel School of Medicine have found that hypoxic conditions are linked to a hypoxia-typic morphotype of the pathogen Aspergillus fumigatus. This morphotype worsens the diseases progression of invasive aspergillosis in a murine model.