In this interview, we speak to Jenn Edwards from the Abigail Wexner Research Institute (OH, USA) about her research using the primary human epithelial cell models to examine Neisseria gonorrhoeae infections, the potential for vaccination against gonorrhea and a possible host-targeted therapy for this infection.
Browsing: Host-pathogen Interaction
Researchers have uncovered a novel mechanism utilized by group A streptococcus that allows it to evade detection by the immune system in infected mice, providing insight for the development of effective countermeasures against this pathogen.
New research indicates that harnessing RNA sensors could allow human cells to be more attuned to killing tuberculosis, presenting an effective means for controlling the spread of the disease.
In this opinion piece we take a look at the interaction of bacteria, phages and the human immune system. asking how these three components each play a role in phage therapy?
Researchers may have discovered how Ebola invades our immune system and disrupts the host immune response.
Rotavirus infection can result in severe-life threatening illness in some individuals, however, new research from a team at Georgia State University (GA, USA), has identified bacteria that could be used to prevent or cure this infection.
Researchers at Dartmouth’s Geisel School of Medicine have found that hypoxic conditions are linked to a hypoxia-typic morphotype of the pathogen Aspergillus fumigatus. This morphotype worsens the diseases progression of invasive aspergillosis in a murine model.
New research shows that hydrogen peroxide released by Streptococcus pneumoniae inhibits key components of the innate immune system. This contributes to the successful pathogen colonization of the host and causes pneumonia.
New research has uncovered that Mycobacterium tuberculosis releases an antacid that remodels phagosomes, preventing immune cells from destroying the bacteria.
A new study has implicated the cytokine interferon gamma as a major contributor of blood–brain barrier breakdown in central nervous system infections.