HIV: new imaging reveals targets on the viral envelope
New research describes the use of small-molecule CD4 mimetic compounds that force HIV to undergo conformational changes, exposing normally hidden parts of the envelope and potential new targets.
Browsing: Imaging
Ebola nucleocapsid modeled to near-atomic resolution
A team from the Okinawa Institute of Science and Technology Graduate University has used cryo-EM to model the nucleocapsid protein of Ebola virus, potentially uncovering novel drug targets.
Could PET imaging provide insights into Zika virus neurological sequelae progression?
In this editorial, the authors assess the insights that could be provided by PET imaging in evaluating and understanding the progression of neurological sequale in Zika virus.
West Nile virus: MRI scans uncover evidence of long-term neurological damage
Research presented at ASTMH has demonstrated long-term neurological damage in those with a history of West Nile virus infection, even in individuals who experienced mild, or no, symptoms.
Microbiome of organs mapped in 3D
Researchers have developed a workflow to enable metabolomic and microbiome data to be mapped onto a 3D organ reconstruction, shedding insights on spatial variations.
First 3D movie of virus depicts key biological processes in replication
For the first time, physicists have created a 3D movie that demonstrates a virus preparing to infect a healthy cell via genomic rearrangement – leading to the potential to better treat an array of human diseases caused by viruses.
Mobile phones create new opportunities for microbiology research and clinical applications
In this editorial, the authors dicuss how mobile phones have the potential to transform traditional uses of imaging, sensing and diagnostic systems, especially for point-of-care applications and field settings.
Novel imaging allows real-time monitoring of dengue infection in the body
Researchers have demonstrated an imaging technique utilizing PET, which allows non-invasive and real-time monitoring of dengue infection in mouse models.
Could the gut microbiome hold the key to neurodegenerative disorders?
A team of UK-based researchers have been awarded a major grant to investigate the relationship between alterations in the gut microbiota and neurodegenerative disorders.