In this review, the authors discuss recent findings on unfolded protein response (UPR) induction/modulation by intracellular parasites in host cells.
Browsing: Immune Response
Improved therapeutic strategies are in urgent need for better control and eradication of tuberculosis. In this editorial, the authors evaluate interleukin-37 as a new molecular target for the therapy of tuberculosis.
Researchers have discovered that compounds altering transmembrane potential in Xenopus laevis may improve resistance to E. coli infection.
A novel, bioinspired antimicrobial treatment, consisting of iodo-thiocyanate complexes, has demonstrated promising results as a bactericidal compound, according to new research.
Researchers have utilized CRISPR/Cas9 technology on human induced pluripotent stem cells to identify genes involved in fighting off Chlamydia trachomatis infections.
Components from bacteria-infecting viruses could allow scientists to create hybrid human antibodies that can target carbohydrate molecules found on bacterial cell surfaces.
Given the ability of the microbiota to instruct the immune system and control the inflammatory response, the authors discuss the potential of targeting the microbiota to improve the immune recovery and dampen inflammation during HIV infection.
Oral delivery of vaccines is an attractive approach but is hampered by a number of challenges. Here, the authors discuss the need to include immunostimulatory adjuvants in oral vaccines to overcome oral tolerance and elicit effector immune responses locally within the intestine.
A Phase I clinical trial has demonstrated two investigational Ebola vaccines generate a durable immune response 1 year after vaccination.
New findings have identified the exact mechanism by which the bacterium Salmonella typhimurium can escape degradation by autophagy.