2020: A molecular odyssey – could artificial intelligence bring in a new age of antibiotic drug discovery?
Using machine-learning, researchers have discovered a new antibiotic that is able to kill bacteria resistant to other antibiotics.
Browsing: Mouse Model
Novel vaccine candidate for Staphylococcus aureus shows 80% efficacy in mice
Research published today in Infection and Immunity suggests a novel vaccine for Staphylococcus aureus may be on the horizon, with the candidate protecting 80% of immunized mice.
Zika: American subtype revealed to have the highest virulence activity in mice
Researchers from the Japanese National Institute of Infectious Disease have identified the American subtype of Zika as the most virulent for each of the contributing characteristics tested, when compared with Pacific and Southeast Asian subtypes.
Could a westernized diet impact sepsis severity and mortality rates?
Findings from a study at Portland State University suggest the severity of sepsis development and the subsequent outcome can be worsened through eating a ‘Western’ diet, high in both sugar and fat.
Micromotor formulation shows promise for oral vaccination
A biomimetic, micromotor vaccine formulation has shown promising results in immunizing against Staphylococcus aureus in mouse models.
Can Candida albicans cross the blood–brain barrier?
Researchers have discovered Candida albicans can cross the blood–brain barrier, triggering an immune response that results in the formation of granuloma-type structures and memory impairments.
Could an mRNA vaccine be protective against emerging tick-borne viruses?
An mRNA-based vaccine has been demonstrated to protect against Powassan virus in mice, in addition to also conferring protection against the more distantly related Langat virus.
Blocking toxin formation – a treatment for Gram-positive pathogens?
Small molecules that block bacterial toxin formation have shown promise against Gram-positive bacteria in mouse models.
Can dietary fiber increase survival in influenza-infected mice?
A high-fiber diet can boost the immune response and increase survival in mice infected with influenza virus, according to new research.
Flu strains may impact healthy brain function in mice
Researchers have identified that two flu strains are associated with changes to hippocampal structure and function in female mice alongside memory impairment – posing a threat to healthy brain function.