What effects can intrapartum antimicrobial use have on the neonatal microbiome development? And could they impact in long-term health?
In this editorial, the authors assess the insights that could be provided by PET imaging in evaluating and understanding the progression of neurological sequale in Zika virus.
In this Editorial from Future Virology the authors discuss maternal immunization as a strategy for preventing neonatal HSV infection.
Maternal nutritional status during pregnancy and infant immune response to routine childhood vaccinations
In this review the authors systematically review the association between maternal nutritional status in pregnancy and infant immune response to childhood vaccines.
Maternal microchimerism (MMc) is a normal part of pregnancy, however, relatively little work has been done exploring the intersection of MMc and infectious disease. Here, Whitney Harrington discusses it’s implications in malaria.
Parechoviruses have been recognized for decades, but the lack of routine diagnostic assays targeting this virus has made it slow for clinical teams to realize the importance of this pathogen as the cause of neonatal and infant sepsis, with possible longer term neurodevelopmental sequelae.
Researchers have discovered that some oligosaccharides from human breast milk may possess antimicrobial and anti-biofilm properties against Group B Streptococcus (GBS).
ST37 Klebsiella pneumoniae: development of carbapenem resistance in vivo during antimicrobial therapy in neonates
Currently, carbapenems are an antibiotic option against MDR K. pneumoniae worldwide, however, carbapenem resistance is being reported on a large scale. This study investigates the mechanism leading to in vivo carbapenem resistance development in Klebsiella pneumoniae.
Widespread use of antibiotics in pregnancy to eradicate Group B Streptococcus has reduced disease in babies, however, could bacteriophage therapy yield the same results but in a more selective manner?