Intrapartum antimicrobial prophylaxis: the yin & yang on the early health foundation
What effects can intrapartum antimicrobial use have on the neonatal microbiome development? And could they impact in long-term health?
Browsing: Neonatal
Could PET imaging provide insights into Zika virus neurological sequelae progression?
In this editorial, the authors assess the insights that could be provided by PET imaging in evaluating and understanding the progression of neurological sequale in Zika virus.
Preventing neonatal herpes infections through maternal immunization
In this Editorial from Future Virology the authors discuss maternal immunization as a strategy for preventing neonatal HSV infection.
Maternal nutritional status during pregnancy and infant immune response to routine childhood vaccinations
In this review the authors systematically review the association between maternal nutritional status in pregnancy and infant immune response to childhood vaccines.
Intergenerational immune interactions: Malaria and maternal microchimerism
Maternal microchimerism (MMc) is a normal part of pregnancy, however, relatively little work has been done exploring the intersection of MMc and infectious disease. Here, Whitney Harrington discusses it’s implications in malaria.
Human parechovirus – an old virus but a new diagnostic target
Parechoviruses have been recognized for decades, but the lack of routine diagnostic assays targeting this virus has made it slow for clinical teams to realize the importance of this pathogen as the cause of neonatal and infant sepsis, with possible longer term neurodevelopmental sequelae.
Oligosaccharides from breast milk could protect against GBS
Researchers have discovered that some oligosaccharides from human breast milk may possess antimicrobial and anti-biofilm properties against Group B Streptococcus (GBS).
ST37 Klebsiella pneumoniae: development of carbapenem resistance in vivo during antimicrobial therapy in neonates
Currently, carbapenems are an antibiotic option against MDR K. pneumoniae worldwide, however, carbapenem resistance is being reported on a large scale. This study investigates the mechanism leading to in vivo carbapenem resistance development in Klebsiella pneumoniae.
Think broad, act narrow: bacteriophage therapy, a targeted solution to GBS?
Widespread use of antibiotics in pregnancy to eradicate Group B Streptococcus has reduced disease in babies, however, could bacteriophage therapy yield the same results but in a more selective manner?