Gene atlas of malaria parasite reveals potential drug and vaccine targets
Scientists from Imperial College London (UK) and the Wellcome Sanger Institute (Cambridge, UK) have mapped…
Browsing: Parasitic Infection
Malaria parasites resistant to artemisinin now prevalent in Africa
Malara parasites showing artemisinin resistance previously seen in South-East Asia have recently emerged in areas of Rwanda in Sub-Saharan Africa. If the mutation causing resistance becomes prevalent across the continent it could have major public health impacts.
Using a novel approach for malaria vaccine development – an interview with Jonathan Kurtis
In this interview we speak to Jonathan Kurtis (Brown University, RI, USA) about the discovery of a parasite protein that provides new insights into how malaria regulates infection levels within its host, along with new possibilities for a broadly effective vaccine and a new class of antimalarial drugs.
Novel parasites and understanding parasite–host interactions – an interview with Sandra Maruyama
In October 2019 researchers from Brazil identified a new parasite, which presented with similar symptoms to visceral leishmaniasis. To discover more about this novel parasite and other parasitic diseases in Brazil, we interviewed Sandra Maruyama from the Federal University of São Carlos (UFSCar; São Paulo, Brazil) about her research and the future of this field.
The Malaria Cell Atlas provides insights into gene clusters and future treatments
Researchers recently profiled the single-cell transcriptomes of thousands of individual parasites to provide the first high-resolution atlas of malaria parasite gene expression across the lifecycle.
Mice, introduced by maritime trade, play a key role in Toxoplasma gondii distribution
The house mouse – introduced by humans via the maritime trade – has dramatically shaped Toxoplasma gondiipopulations in West Africa and around the world, according to new research.
Argentina and Algeria certified malaria-free by the WHO
Argentina and Algeria have officially been certified as free of malaria by the WHO, both becoming the second country in their respective regions to achieve this certification.
RTS,S vaccine to enter Phase IV trials in Malawi, Kenya and Ghana
A large-scale trial of RTS,S – the world’s first malaria vaccine to provide partial protection – is due to commence in Malawi, Kenya and Ghana.
ECCMID19: 1 million new malaria cases estimated in Venezuela in 2018
A huge upsurge in malaria cases has been caused by Venezuela’s socioeconomic and political crisis, undoing years of progress and endangering neighbouring countries, according to research presented at ECCMID.
Experimental antimalarial shows promise in human challenge study
A single, oral dose of antimalarial DSM265 has cleared seven volunteers of a Plasmodium falciparum infection, according to the trial from the Medicines for Malaria Venture.