CNS infections: interferon gamma could play a role in blood–brain barrier breakdown
A new study has implicated the cytokine interferon gamma as a major contributor of blood–brain barrier breakdown in central nervous system infections.
Browsing: Pathogenesis
Computational model reveals how prions replicate
A new computational model has revealed the mechanism of replication in prions, potentially opening new avenues for drug development against prion diseases.
ECCMID19: Some individuals shed flu virus before symptoms appear
Research presented at ECCMID examining influenza transmission has discovered that a substantial proportion of patients and healthcare workers shed the flu virus before clinical symptoms appear.
What impact do microbiome metabolites have on EHEC infections?
Microbiome metabolites have been discovered to enhance colon injury in human EHEC infections in a human–mouse comparative study, accounting for species-specific differences in infection tolerance.
Epstein-Barr virus and schizophrenia linked by abnormal immune response
Individuals with schizophrenia also have higher level of antibodies against the Epstein-Barr virus, according to new research.
Vaccinia virus hijacks host cell motility to aid spread
New research has suggested that vaccinia viruses trick infected host cells into activating their cell movement mechanism, rapidly spreading the virus.
ASM Microbe: How do bacteria ‘eat’ bone to sustain invasive infection?
A recent study has revealed the metabolic pathway that bacteria use to survive in bone, which could potentially act as a target for the development of new antimicrobial compounds.
Do HIV-associated neurological disorders have shared mechanisms with Alzheimer’s disease?
New research has suggested that a protein involved in Alzheimer’s disease may also be implicated in HIV-associated neurological disorders, suggesting Alzheimer’s therapies may benefit a subset of HIV patients.
Infographic: The microbiome and infectious diseases
In our latest infographic we provide a visual snapshot of the infections and immune processes that have been linked with the microbiome thus far, explaining some of the evidence
Investigating heat-shock gene htpG and the production of virulence factors in Pseudomonas aeruginosa
This study, recently published in Future Microbiology, aimed to study the effects of encoded heat-shock protein 90 homolog (htpG) on the selected virulence factors responsible for pathogenesis and biofilm formation of P. aeruginosa.
