Scientists discover a new powerful protective immune pathway triggered by ion channels in airway epithelial cells.
A new study has identified the role of T cell protein, Tim-1, in initiating the inflammatory response that is central to Ebola pathogenesis and disease severity.
New research has uncovered that a neuropathogenic virus exploits the neuronal granule system for the transport of viral genomic RNA in dendrites, resulting in reproduction of the virus and severe neurological disease.
The pathogenicity of T. marneffei depends on the ability of the fungus to survive the killing process and replicate inside the host macrophage cells. This paper summarizes factors relating to the stress responses that contribute to the intracellular survival of T. marneffei
Researchers from the Washington University School of Medicine examined the role of yersiniabactin (Ybt) in copper import in bacteria. Their findings indicate that bacteria are able to utilize Ybt to obtain copper as a source of nutrition.
Researchers have demonstrated that a licenced malaria drug may protect fetuses from Zika infection in mice models by altering the autophagy pathway.
Researchers investigating Ebola virus have uncovered the function of delta protein, which is released in high levels during infection, and findings suggest it could play a crucial role in disease pathology.
Researchers have discovered that compounds altering transmembrane potential in Xenopus laevis may improve resistance to E. coli infection.
Researchers have discovered a variation in the human red blood cell receptor glycophorin that appears to reduce the risk of severe malaria by 40%.
Although understanding of Ebola virus pathogenesis has rapidly increased recently, many questions relating to the role of the vascular system remain unanswered. The authors here discuss how Ebola virus infection can cause endothelial dysfunction and coagulopathy.