Researchers investigating Ebola virus have uncovered the function of delta protein, which is released in high levels during infection, and findings suggest it could play a crucial role in disease pathology.
Researchers have discovered that compounds altering transmembrane potential in Xenopus laevis may improve resistance to E. coli infection.
Researchers have discovered a variation in the human red blood cell receptor glycophorin that appears to reduce the risk of severe malaria by 40%.
Although understanding of Ebola virus pathogenesis has rapidly increased recently, many questions relating to the role of the vascular system remain unanswered. The authors here discuss how Ebola virus infection can cause endothelial dysfunction and coagulopathy.
New findings have identified the exact mechanism by which the bacterium Salmonella typhimurium can escape degradation by autophagy.
Researchers have uncovered the role of inflammasome activation in leishmaniasis progression and severity, demonstrating that inhibiting these pathways may present a potential avenue for future treatments.
Researchers have utilized a novel mouse model to demonstrate that Zika infection during early pregnancy could lead to higher risk of miscarriage in addition to thin brain tissue and brain inflammation in infants.
Researchers have uncovered a mechanism utilized by Zika virus to cross the placental barrier; this has provided an insight into the virus’ ability to cause birth defects such as microcephaly
Researchers have identified a crucial mechanism by which the chikungunya virus infects host cells and mediates disease severity. This could present a future treatment target for both chikungunya and related viruses.
The putative autophagy regulator Atg7 affects the physiology and pathogenic mechanisms of Cryptococcus neoformans
The most common cause of fungal meningitis for people with weak immune systems is Cryptococcus. This study aims to investigate the involvement of the autophagy protein 7 in the physiology and pathogenic potential of Cryptococcus neoformans.