New findings have identified the exact mechanism by which the bacterium Salmonella typhimurium can escape degradation by autophagy.
Researchers have uncovered the role of inflammasome activation in leishmaniasis progression and severity, demonstrating that inhibiting these pathways may present a potential avenue for future treatments.
Researchers have utilized a novel mouse model to demonstrate that Zika infection during early pregnancy could lead to higher risk of miscarriage in addition to thin brain tissue and brain inflammation in infants.
Researchers have uncovered a mechanism utilized by Zika virus to cross the placental barrier; this has provided an insight into the virus’ ability to cause birth defects such as microcephaly
Researchers have identified a crucial mechanism by which the chikungunya virus infects host cells and mediates disease severity. This could present a future treatment target for both chikungunya and related viruses.
The putative autophagy regulator Atg7 affects the physiology and pathogenic mechanisms of Cryptococcus neoformans
The most common cause of fungal meningitis for people with weak immune systems is Cryptococcus. This study aims to investigate the involvement of the autophagy protein 7 in the physiology and pathogenic potential of Cryptococcus neoformans.
Foodborne enterotoxigenic Escherichia coli: from gut pathogenesis to new preventive strategies involving probiotics
Could probiotics be used to treat Enterotoxigenic Escherichia coli (ETEC)? This review discusses ETEC pathogenesis, its modulation by human gastrointestinal cues and novel preventive strategies such as probiotics.
Researchers have discovered that a component of the Staphylococcus aureus cell wall appears to be responsible for elevated virulence in community-associated MRSA infections. This mechanism could present a target for novel anti-infective strategies.