Imaging study reveals how malaria parasites bypass antimalarial drugs
Published in Nature, new research elucidates the mechanism behind malarial resistance to piperaquine and suggests how this knowledge could be used to combat its spread.
Browsing: Protein Interaction
Ebola: newly identified host factor could be a target for intervention
Researchers have identified that the Ebola virus recruits a host enzyme, PP2A-B56, for replication, demonstrating that inhibiting this pathway could be a target for drug discovery.
Which host proteins interact with chronic viruses?
Researchers have established a map of protein interactions for the replication machinery of chronic viruses, shedding insight into viral strategies and uncovering potential drug targets.
Discovery of key molecules responsible for immune evasion by Plasmodium falciparum
Scientists have revealed proteins, termed RIFINs, expressed on the surface of infected erythrocytes that may help the malaria parasite to suppress the host immune response, leading to severe infection.
Promising peptide fusion inhibitors developed against influenza
Researchers have designed potent peptide fusion inhibitors that can neutralize a broad range of influenza viruses and could present a promising avenue for future therapeutics.
Study elucidates the role of hGBP1 in pathogen response
Researchers have gained new insights into the role of human guanylate-binding protein 1 (hGBP1) in pathogen response, uncovering a role in membrane tethering.