This opinion piece looks at the impact a precision (or personalized) medicine approach could have in sepsis, including early and accurate microbiologic diagnosis, determining the host immune response signature and assessing individual response to treatment.
New research suggests that sepsis may be associated with one in five deaths, double the previous estimate, but overall trends suggest incidence and mortality may be decreasing.
A study published today in the Journal of the America Medical Informatics Association has demonstrated that a new digital sepsis monitoring system implemented in three Imperial College Healthcare NHS Trust (London, UK) hospitals lowered the odds of death from sepsis by 24%.
Sepsis, a condition associated with significant morbidity and mortality, has been increasingly associated with the…
In this interview we speak to Pinaki Panigrahi about his work using probiotics as a preventative strategy against sepsis in neonates. In addition, he comments on the impact of probiotics for other infections and some of the skepticism surrounding some microbiome research.
New research has identified four novel sepsis phenotypes, suggesting these could be relevant for understanding the heterogeneity of treatment effects and help to explain recent clinical trial failures.
ECCMID19: Mortality rate in bloodstream infections varies hugely depending on the causative organism
Research presented at ECCMID has highlighted large variations in mortality rate associated with different bloodstream infections, as well as the threat posed by these infections.
A computer-aided model that uses routinely collected data could identify the early symptoms of sepsis, according to new research.
A new rapid microelectrode device for the earlier diagnosis of sepsis has been developed by researchers at the University of Strathclyde.
Findings from a study at Portland State University suggest the severity of sepsis development and the subsequent outcome can be worsened through eating a ‘Western’ diet, high in both sugar and fat.