First chlamydia vaccine to reach Phase I trial appears safe and immunogenic
The first chlamydia vaccine to reach Phase I clinical trials has been observed to be safe and immunogenic in 35 women.
Browsing: Sexually Transmitted
IAS 2019: highlights and headlines
Find out more about the headlines from the 10th International AIDS Society Conference on HIV Science (IAS 2019) in our round-up of conference news.
CRISPR and long-acting therapies eliminate HIV DNA from the genome in animal models
A new study using CRISPR-Cas9 and long-acting slow-effective release antiretroviral therapy has reported the elimination of replication-competent HIV-1 DNA from the genomes of living animals for the first time.
STIs: research estimates over 1 million new cases occur every day
A report analyzing the prevalence and incidence of chlamydia, gonorrhea, trichomoniasis and syphilis for 2016 has reported that rates of these four curable sexually transmitted infections remain high, estimating 376.4 million cases in 2016.
Early antiretroviral treatment could help develop long-term immune memory
Early antiretroviral treatment in people with HIV infection could allow the generation of more functional and persistent CD8 T cell responses. The results, which suggest a long-term immune memory, could have implications for HIV vaccine development.
Who should take the lead in prescribing PrEP?
Healthcare practitioners have split opinions on whether primary care doctors or other providers should take the lead on prescribing PrEP for HIV prevention, according to new research.
HIV: new imaging reveals targets on the viral envelope
New research describes the use of small-molecule CD4 mimetic compounds that force HIV to undergo conformational changes, exposing normally hidden parts of the envelope and potential new targets.
HIV remission achieved in second patient ever
A second individual has achieved sustained remission from HIV-1 after ceasing antiretroviral treatment, according to researchers from University College London. Following a hematopoietic stem cell transplant and chemotherapy the patient has had undetectable viral loads for 18 months.
Could gene therapy be an effective treatment for chlamydia?
New research has developed a nanoparticle formulation that can knock down a key chlamydia binding protein and simultaneously induce autophagy – showing promise against this infection.
A peek behind the paper – Darrell Tan on the mechanisms and management of HIV PrEP failure
Take a look behind the scenes of a recent Future Virology paper as we ask author Darrell Tan about the potential of pre-exposure prophylaxis (PrEP) for HIV prevention, PrEP failure and what research is needed in the field.
