New drugs with antifungal action need to be developed. Here, the authors investigate the antifungal activity of MOL3, a small molecule that was selected by virtual screening, against Candida spp.
Recently, the use of small molecules produced by bacteria became a prominent strategy of biofilm dispersal. Here, the authors discuss small molecules that interfere with biofilm formation, focusing on the complex mode of action and applications of D-amino acids.
Researchers have reported a small-molecule inhibitor of Candida albican protein Bdf1 and demonstrated the compound yields decreased fungal viability, suggesting a possible future antifungal.
