MERS vaccine success in mice suggests potential for COVID-19 vaccine development
A vaccine against MERS has shown promise in mouse models, potentially aiding the development of a vaccine against COVID-19.
Browsing: Vaccines
COVID-19: First patients dosed in Phase I vaccine trial
Moderna has announced that the first participants have been dosed in a Phase I study of their mRNA candidate vaccine against SARS-CoV-2, the virus that causes COVID-19.
A peek behind the paper – Muhammad Faheem on dengue virus proteins as potential drug targets
Take a look behind the scenes of a recent Future Virology editorial entitled, ‘An insight into dengue virus proteins as potential drug/vaccine targets’, as we ask author Muhammad Faheem about recent advances in understanding dengue proteins and where the next 5–10 years could take us.
Universal vaccines: A holy grail for the flu?
In this blog, we review some of the main targets of universal vaccines and the key challenges to their successful implementation.
Could obesity promote virulence in influenza?
A mouse study has revealed that obesity may be one factor explaining the significant amount of variation in the influenza virus each year, likely due to an impaired interferon defense response.
Clinical trial of experimental HIV vaccine halted
The National Institute of Allergy and Infectious Diseases has stopped administering an experimental HIV vaccine in the South Africa HVTN 702 clinical trial, after an independent data and safety monitoring board has found that the vaccine is ineffective at preventing HIV infection.
Could tailor-made vaccines halve rates of serious Streptococcus pneumoniae infection?
Optimizing vaccine models for Streptococcus pneumoniae suggests that vaccine programs need to be tailored to target specific subgroups including age and geographical region.
Changing the administration of the BCG vaccine could improve efficacy
Administering the BCG vaccine intravenously, as opposed to intradermally, could improve the efficacy of the immunization according to new research in macaque models.
HIV vaccine may be possible through coaxing the immune system to select key antibodies
Using animal models, researchers have discovered that antibodies can be coaxed into proliferating and targeting HIV.
Alternatives to antibiotics for drug-resistant gonorrhea – an interview with Jenn Edwards
In this interview, we speak to Jenn Edwards from the Abigail Wexner Research Institute (OH, USA) about her research using the primary human epithelial cell models to examine Neisseria gonorrhoeae infections, the potential for vaccination against gonorrhea and a possible host-targeted therapy for this infection.
