A team from the Okinawa Institute of Science and Technology Graduate University has used cryo-EM to model the nucleocapsid protein of Ebola virus, potentially uncovering novel drug targets.
Browsing: Viral Proteins
At the recent Microbiology Society Annual Conference (10–12 April, Birmingham, UK) we spoke to Mark Wass about his work on Ebolaviruses in which he’s delved into the molecular determinants of the virus’s pathogenicity.
Researchers have established a map of protein interactions for the replication machinery of chronic viruses, shedding insight into viral strategies and uncovering potential drug targets.
Scientists have revealed that a human protein – identified as YTHDF2 – could prevent cancer by restricting the human herpes virus 8, otherwise known as Kaposi’s sarcoma-associated herpesvirus.
In a recently published study, researchers have utilized spectroscopy techniques to provide an in-depth understanding of the atomic interaction that occurs when viral buds are released from the host cell’s membrane after infection.
According to a recently published study, the effectiveness of the H3N2 vaccine could be attributed to the egg-based vaccine production process, which may ultimately render the vaccine to be less effective in humans.
Researchers have revealed that arteriviruses may produce more mRNAs and proteins than previously understood – a finding that could provide insight on how the virus may potentially evolve to infect humans.
Recombinase polymerase amplification: a promising point-of-care detection method for enteric viruses
This report reviews the use of recombinase polymerase amplification for virus detection, showing that the method has favorable fundamental properties supporting its promise for rapid point-of-care detection of enteric viruses.
Researchers have identified a new treatment approach for acute HIV-infected patients, which targets human proteins rather than the virus.
Characterizing the ligand-binding landscape of Zika NS3 helicase-promising lead compounds as potential inhibitors
This study from Future Virology, aims to provide insight into the binding features of the ATPase and ssRNA sites of the NS3 helicase.